Holt J A
Med Hypotheses. 1980 Feb;6(2):145-92. doi: 10.1016/0306-9877(80)90081-x.
There is evidence to suggest that the extra nuclear cell constituents are the part of the cell which contains all the biochemical mechanisms responsible for implementing all cell functions. These functions include control of cell division, growth, response to injury, replacement of effete cells, maintenance of anatomical and spatial cellular relations and specific cellular function and structure. The energy to perform these functions is derived from the aerobic metabolism of glucose. The energy required for nuclear division appears to be wholly or partly derived from the anaerobic metabolism of glucose. Ethyl alcohol interferes with the aerobic metabolic pathways and thus disrupts or diminishes all aerobically activated cell functions. The speed of all activities motivated by aerobic glycolysis can be increased by appropriate electrical stimulations delivered from any of a range of electromagnetic radiation frequencies tested. In addition to the stimulant effect on aerobic metabolic processes, 434 MHz can stimulate the anaerobic glucose metabolism of cancer with consequent stimulation of cancer growth rate. 434 MHz appears to deliver energy to the anaerobic cancer metabolism by causing a resonance phenomenon amongst one or more of the substrates which comprise the first few stages of glycolysis. This phenomenon permits the selective delivery of electromagnetic radiation energy to cancer cells which, if sufficiently intense, causes injury to cancer cells without harm to the normal cells except when the latter are in the phase of anaerobic metabolism which occurs at some stage of the mitotic cycle. Streptokinase, ethanol and glucose analogues increase the lethal effects on cancers undergoing therapy with 434 MHz radiation and observations of such responses suggest a theoretical basis to explain the rare spontaneous remissions of human cancer. Cancer appears to protect its glucose supplies by elevating the blood glucose levels above normal and by some mechanism which reduces the effectiveness of the body's control of its fasting glucose level. The serum fibrinogen level rises when cancer involves the abdominal viscerae, particularly the liver. A raised serum fibrinogen level appears to be a direct indication that the liver must be included in the treatment regime if longer survival is desired. If the level cannot be corrected then death of that individual appears assured.
有证据表明，细胞核外的细胞成分是细胞的一部分，它包含负责执行所有细胞功能的所有生化机制。这些功能包括控制细胞分裂、生长、对损伤的反应、衰老细胞的替代、维持细胞的解剖和空间关系以及特定的细胞功能和结构。执行这些功能所需的能量来自葡萄糖的有氧代谢。核分裂所需的能量似乎全部或部分来自葡萄糖的无氧代谢。乙醇会干扰有氧代谢途径，从而破坏或减少所有有氧激活的细胞功能。通过测试的一系列电磁辐射频率中的任何一种进行适当的电刺激，可以提高有氧糖酵解驱动的所有活动的速度。除了对有氧代谢过程的刺激作用外，434兆赫还可以刺激癌症的无氧葡萄糖代谢，从而刺激癌症的生长速度。434兆赫似乎通过在构成糖酵解前几个阶段的一种或多种底物之间引起共振现象，将能量传递给癌症的无氧代谢。这种现象允许将电磁辐射能量选择性地传递给癌细胞，如果强度足够大，会对癌细胞造成损伤，而不会对正常细胞造成伤害，除非后者处于有丝分裂周期某个阶段发生的无氧代谢阶段。链激酶、乙醇和葡萄糖类似物会增加434兆赫辐射治疗癌症的致死效果，对这种反应的观察为解释人类癌症罕见的自发缓解提供了理论基础。癌症似乎通过将血糖水平提高到正常水平以上，并通过某种降低身体对空腹血糖水平控制有效性的机制来保护其葡萄糖供应。当癌症累及腹部脏器，特别是肝脏时，血清纤维蛋白原水平会升高。血清纤维蛋白原水平升高似乎直接表明，如果希望延长生存期，治疗方案中必须包括肝脏。如果该水平无法纠正，那么该个体似乎必死无疑。
