细菌对真核细胞的黏附：淋巴细胞结合突变体的分离
Bacterial adherence to eucaryotic cells: isolation of lymphocyte-binding mutants.
作者信息
Mayer E P, Teodorescu M
出版信息
Infect Immun. 1980 Jul;29(1):66-9. doi: 10.1128/iai.29.1.66-69.1980.
Abstract
A procedure for obtaining bacterial mutants that bind to eucaryotic cells is described. This procedure takes advantage of the ability of the mutants to obtain a required nutrient from the eucaryotic cells. We used this procedure to isolate mutants of Escherichia coli that bind to mouse lymphocytes. We show that the mutants identify some immunoglobulin-bearing lymphocytes and some non-immunoglobulin-bearing lymphocytes.
摘要
描述了一种获得与真核细胞结合的细菌突变体的方法。该方法利用了突变体从真核细胞获取所需营养物质的能力。我们使用此方法分离出了与小鼠淋巴细胞结合的大肠杆菌突变体。我们发现这些突变体能够识别一些携带免疫球蛋白的淋巴细胞和一些不携带免疫球蛋白的淋巴细胞。
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