Mukherjee R, Mahadevan P R, Antia N H
Int J Lepr Other Mycobact Dis. 1980 Jun;48(2):189-92.
Schwann cells that contain M. leprae fail to incorporate DNA precursor, indicating blockage of DNA synthesis. Such a block could lead to no proliferation of Schwann cells, an essential requirement for successful association with axons and consequent myelination.
含有麻风杆菌的施万细胞无法掺入DNA前体,这表明DNA合成受阻。这种阻断可能导致施万细胞无法增殖,而施万细胞增殖是与轴突成功结合并随后进行髓鞘形成的必要条件。