Law S W, Gibbons W, Poindexter A N
J Reprod Med. 1980 May;24(5):197-201.
From 1974 through 1978, 59 insulin-dependent diabetic patients were treated in a university-affiliated general hospital. They were managed primarily as outpatients with hospitalization for regaining glucose control and/or in the treatment of obstetric complications. In 1976 a special clinic for pregnant diabetic patients was established. The 26 patients treated during the clinic's first two years are compared to 33 treated in the preceding 2 1/2 years. The significant difference between the two groups was the improvement in the number of patients whose cooperation was good, 67% to 85% (p less than 0.05), and the reduction of perinatal morbidity and mortality. The perinatal mortality rate was 18% and 8% in the preclinic group (group I) and the clinic group (group II), respectively. The combined perinatal morbidity and mortality was reduced from 36% to 15%, respectively, in groups I and II (p less than 0.01). A constant rate of 3.2% perinatal mortality was observed in the obstetric population during the study period.
1974年至1978年期间，一家大学附属医院对59名胰岛素依赖型糖尿病患者进行了治疗。他们主要作为门诊患者进行管理，住院治疗以恢复血糖控制和/或治疗产科并发症。1976年设立了一个糖尿病孕妇特别诊所。将该诊所头两年治疗的26名患者与前两年半治疗的33名患者进行了比较。两组之间的显著差异在于合作良好的患者数量有所改善，从67%提高到85%（p小于0.05），围产期发病率和死亡率降低。门诊前组（第一组）和门诊组（第二组）的围产期死亡率分别为18%和8%。第一组和第二组的围产期发病率和死亡率总和分别从36%降至15%（p小于0.01）。在研究期间，产科人群的围产期死亡率恒定为3.2%。
