Olson R J, Mattingly T P, Waltman S R, Kaufman H E
Ophthalmology. 1980 Jul;87(7):680-6. doi: 10.1016/s0161-6420(80)35187-7.
Sixty-four consecutive patients with aphakic penetrating keratoplasty and penetrating keratoplasty combined with intracapsular cataract extraction were reviewed in a prospective fashion with a minimum of a one-year follow-up. Five were lost to follow-up. There were seven graft failures at the end of one year. Five of these were from 11 patients who underwent second operations because of failed grafts. Visual acuity was 20/80 or better in 29 of the patients. Pathology accounted for decreased visual acuity in all of those with visual acuity less then 20/80. Problems wre macular degeneration in 11 of the 23 patients with poor visual acuity (48%); marked cystoid macular edema in four patients (17%), advanced glaucoma in three patients (13%) and amblyopia in three patients (13%). Graft size had no significant effect on visual acuity. In terms of the final refractive error and astigmatism, there were no significant differences seen in those in whom a larger donor was used compared with those in whom a donor the same size as the recipient opening was used. Aphakic penetrating keratoplasty has shown outstanding technical success with poor visual acuity representing a difficulty in screening for non-corneal pathology. With an otherwise normal eye, the chances for excellent optical success are very good at the present time with modern techniques in aphakic penetrating keratoplasty.
对64例接受无晶状体穿透性角膜移植术以及穿透性角膜移植术联合囊内白内障摘除术的连续患者进行了前瞻性研究，随访时间至少为一年。5例失访。一年后有7例移植失败。其中5例来自11例因移植失败而接受二次手术的患者。29例患者的视力达到20/80或更好。病理学分析显示，所有视力低于20/80的患者视力下降均与病理学因素有关。视力不佳的23例患者中，11例（48%）存在黄斑变性；4例（17%）有明显的黄斑囊样水肿；3例（13%）患有晚期青光眼；3例（13%）有弱视。移植片大小对视力无显著影响。在最终屈光不正和散光方面，使用较大供体的患者与使用与受体开口大小相同的供体的患者之间没有显著差异。无晶状体穿透性角膜移植术在技术上已取得显著成功，但视力不佳表明在筛查非角膜病理学方面存在困难。在其他方面正常的眼睛中，运用现代无晶状体穿透性角膜移植技术，目前获得极佳光学效果的机会很大。
