胰岛素样肽刺激人类成纤维细胞的代谢，但不刺激其增殖。 - Suppr

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超能文献

Insulin-like peptides stimulate metabolism but not proliferation of human fibroblasts.

作者信息

Harley C B, Goldstein S, Posner B I, Guyda H J

出版信息

Am J Physiol. 1980 Aug;239(2):E125-31. doi: 10.1152/ajpendo.1980.239.2.E125.

DOI:10.1152/ajpendo.1980.239.2.E125

PMID:6996491

Abstract

摘要

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Insulin-like peptides stimulate metabolism but not proliferation of human fibroblasts.胰岛素样肽刺激人类成纤维细胞的代谢，但不刺激其增殖。

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Stimulation of DNA synthesis in human fibroblasts by a human nonsuppressible insulin-like protein (NSILP).一种人类非抑制性胰岛素样蛋白（NSILP）对人成纤维细胞中DNA合成的刺激作用。

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Dissociation of increased hexose transport from initiation of fibroblast proliferation.己糖转运增加与成纤维细胞增殖起始的解离。

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Stimulation of density-inhibited cell cultures by insulin.胰岛素对密度抑制细胞培养物的刺激作用。

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Regulation of amino acid uptake and deoxyribonucleic acid synthesis in isolated human fetal fibroblasts and myoblasts: effect of human placental lactogen, somatomedin-C, multiplication-stimulating activity, and insulin.人胎儿成纤维细胞与成肌细胞中氨基酸摄取及脱氧核糖核酸合成的调节：人胎盘催乳素、生长调节素-C、增殖刺激活性及胰岛素的作用

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DNA synthesis in human fibroblasts: stimulation by insulin and by nonsuppressible insulin-like activity (NSILA-S).人成纤维细胞中的DNA合成：胰岛素和不可抑制的胰岛素样活性（NSILA-S）的刺激作用。

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Effects of chlorpromazine and actinomycin D on uptake and incorporation of certain amino acids, hypoxanthine and thymidine in cultures of human skin epithelial cells.氯丙嗪和放线菌素D对人皮肤上皮细胞培养物中某些氨基酸、次黄嘌呤和胸腺嘧啶摄取及掺入的影响。

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Early cellular responses to diverse growth stimuli independent of protein and RNA synthesis.早期细胞对多种生长刺激的反应，与蛋白质和RNA合成无关。

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Insulin-like growth factors I and II: some biological actions and receptor binding characteristics of two purified constituents of nonsuppressible insulin-like activity of human serum.

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引用本文的文献

Decreased sensitivity of old and progeric human fibroblasts to a preparation of factors with insulinlike activity.老年和早衰人类成纤维细胞对具有胰岛素样活性的因子制剂的敏感性降低。

J Clin Invest. 1981 Oct;68(4):988-94. doi: 10.1172/jci110353.

Regulation of glycosaminoglycan synthesis by thyroid hormone in vitro.甲状腺激素在体外对糖胺聚糖合成的调节

J Clin Invest. 1982 Nov;70(5):1066-73. doi: 10.1172/jci110694.

Dexamethasone regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts. Similar effects of glucocorticoid and thyroid hormones.地塞米松对培养的人皮肤成纤维细胞中糖胺聚糖合成的调节作用。糖皮质激素和甲状腺激素的类似作用。

J Clin Invest. 1984 Dec;74(6):2157-63. doi: 10.1172/JCI111642.

Serum glucocorticoids have persistent and controlling effects on insulinlike growth factor I action under serum-free assay conditions in cultured human fibroblasts.在培养的人成纤维细胞的无血清检测条件下，血清糖皮质激素对胰岛素样生长因子I的作用具有持续的调控作用。

In Vitro Cell Dev Biol. 1989 Jun;25(6):521-7. doi: 10.1007/BF02623564.

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