Wiltrakis M G, Rahimtoola S H, Harlan B J, DeMots H
Chest. 1978 Oct;74(4):411-3. doi: 10.1378/chest.74.4.411.
Three patients with porcine atrioventricular valves (two mitral, one tricuspid) with diastolic rumbles and presystolic murmurs are presented. Full hemodynamic and angiographic studies demonstrated moderate to severe prosthetic stenosis, even in the one patient who was minimally symptomatic. Diastolic murmurs across atrioventricular porcine heterografts indicate prosthetic stenosis until proved otherwise by full hemodynamic and angiographic studies. If the studies indicate normal function of the device and calculated prosthetic valve area that is small for the patient, then it must be recognized that the device is hemodynamically "stenotic" for that particular patient (valve prosthesis--patient mismatch).
本文报告了3例植入猪主动脉瓣（2例二尖瓣，1例三尖瓣）的患者，伴有舒张期隆隆样杂音和收缩期前杂音。全面的血流动力学和血管造影研究表明存在中度至重度人工瓣膜狭窄，即使是症状最轻的1例患者也是如此。除非通过全面的血流动力学和血管造影研究另有证实，否则跨房室猪异种移植物的舒张期杂音提示人工瓣膜狭窄。如果研究表明装置功能正常，但计算得出的人工瓣膜面积对于患者来说较小，那么必须认识到该装置对该特定患者在血流动力学上是“狭窄的”（人工瓣膜-患者不匹配）。
