Mirro M J, Phyhel H J, Wann L S, Weyman A E, Tavel M E, Stewart J
Chest. 1978 Feb;73(2):189-92. doi: 10.1378/chest.73.2.189.
Fourteen of 22 patients (64%) with normally functioning porcine prosthetic valves in the mitral position had apical diastolic rumbles on phonocardiogram and by auscultation. Six (27%) had opening snaps. Factors necessary for the production of a diastolic rumble appear to include central flow, a flexible stent, and the presence of biologic material. Clinicians should be aware that diastolic murmurs and snaps occur in the normally functioning porcine valve.
二尖瓣位猪生物瓣功能正常的22例患者中，14例（64%）心音图及听诊有舒张期心尖隆隆样杂音。6例（27%）有开瓣音。产生舒张期杂音的必要因素似乎包括中心血流、可弯曲的支架以及生物材料的存在。临床医生应意识到，功能正常的猪生物瓣会出现舒张期杂音和开瓣音。
