DiMarco A F, Montenegro H, Payne C B, Kwon K H
Chest. 1978 Oct;74(4):464-5. doi: 10.1378/chest.74.4.464.
Papillomas are rare tumors of the respiratory tract, which are usually considered benign. We studied a male patient with adult onset of squamous papillomatosis involving both the trachea and the bronchi, with malignant degeneration. When we obtained specimens bronchoscopically, only the bronchial lesions showed carcinomatous changes. Thoracotomy demonstrated carcinoma in the tracheal lesion as well. We conclude that transbronchoscopic biopsy may be inadequate in the evaluation of papillomatosis.
乳头状瘤是呼吸道的罕见肿瘤，通常被认为是良性的。我们研究了一名成年男性患者，其患有累及气管和支气管的成人型鳞状乳头状瘤病，并发生了恶性变。当我们通过支气管镜获取标本时，仅支气管病变显示出癌变。开胸手术显示气管病变也存在癌变。我们得出结论，经支气管活检在评估乳头状瘤病时可能并不充分。
