苯巴比妥和β-萘黄酮对雄性和雌性大鼠肝脏及肾脏在体外将环磷酰胺激活为致突变代谢物的影响。 - Suppr | 超能文献

Effects of phenobarbital and beta-naphthoflavone on the activation of cyclophosphamide to mutagenic metabolites in vitro by liver and kidney from male and female rats.

作者信息

Hales B F, Jain R

出版信息

Biochem Pharmacol. 1980 Jul 15;29(14):2031-7. doi: 10.1016/0006-2952(80)90488-8.

DOI:10.1016/0006-2952(80)90488-8

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Effects of phenobarbital and beta-naphthoflavone on the activation of cyclophosphamide to mutagenic metabolites in vitro by liver and kidney from male and female rats.苯巴比妥和β-萘黄酮对雄性和雌性大鼠肝脏及肾脏在体外将环磷酰胺激活为致突变代谢物的影响。

Biochem Pharmacol. 1980 Jul 15;29(14):2031-7. doi: 10.1016/0006-2952(80)90488-8.

2

Modification of the mutagenicity and teratogenicity of cyclophosphamide in rats with inducers of the cytochromes P-450.细胞色素P - 450诱导剂对大鼠体内环磷酰胺致突变性和致畸性的影响

Teratology. 1981 Aug;24(1):1-11. doi: 10.1002/tera.1420240102.

3

Characteristics of the activation of cyclophosphamide to a mutagen by rat liver.大鼠肝脏将环磷酰胺激活为诱变剂的特性。

Biochem Pharmacol. 1980 Feb;29(2):256-9. doi: 10.1016/0006-2952(80)90338-x.

4

Mutagenic activation of 2,4-diaminoanisole and 2-amino-fluorene by isolated rat liver nuclei and microsomes.

Chem Biol Interact. 1980 Jul;31(1):35-49. doi: 10.1016/0009-2797(80)90137-4.

5

Effects of phenobarbital, 3-methylcholanthrene and beta-naphthoflavone pretreatment on mouse liver microsomal enzymes and on metabolite patterns of benzo[a]pyrene.苯巴比妥、3-甲基胆蒽和β-萘黄酮预处理对小鼠肝脏微粒体酶及苯并[a]芘代谢物模式的影响。

Biochem Pharmacol. 1981 Jun 1;30(11):1337-43. doi: 10.1016/0006-2952(81)90318-x.

6

Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.不同形式的细胞色素P450在人类肝脏微粒体中将前诱变剂6-氨基 Chrysene激活为遗传毒性代谢物中的作用。

Carcinogenesis. 1993 Jul;14(7):1271-8. doi: 10.1093/carcin/14.7.1271.

7

Influence of Aroclor 1254, phenobarbital, beta-naphthoflavone, and ethanol pretreatment on the biotransformation of cyclophosphamide in male and female rats.

Toxicology. 1996 Aug 16;112(2):141-50. doi: 10.1016/0300-483x(96)03398-7.

8

Aging modifies the expression of hepatic microsomal cytochromes P-450 after pretreatment of rats with beta-naphthoflavone or phenobarbital.在用β-萘黄酮或苯巴比妥预处理大鼠后，衰老会改变肝微粒体细胞色素P-450的表达。

Exp Gerontol. 1986;21(2):65-73. doi: 10.1016/0531-5565(86)90054-9.

9

Differences in the effects of model inducers of cytochrome P450 on the biotransformation of scoparone in rat and hamster liver.细胞色素P450模型诱导剂对滨蒿内酯在大鼠和仓鼠肝脏中生物转化作用的差异。

Arch Toxicol. 1993;67(2):92-7. doi: 10.1007/BF01973677.

10

Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).在一株过表达O - 乙酰转移酶的鼠伤寒沙门氏菌菌株（NM2009）中，不同形式的大鼠肝脏细胞色素P450将6 - 氨基chrysene激活为基因毒性产物。

Biochem Pharmacol. 1992 Sep 1;44(5):913-20. doi: 10.1016/0006-2952(92)90123-z.

引用本文的文献

1

Effects of acute or chronic polychlorinated biphenyl ingestion on maternal metabolic homeostasis and on the manifestations of embryotoxicity caused by cyclophosphamide in mice.急性或慢性摄入多氯联苯对小鼠母体代谢稳态及环磷酰胺所致胚胎毒性表现的影响。

Arch Toxicol. 1985 Jun;57(2):104-13. doi: 10.1007/BF00343119.

2

Cyclophosphamide metabolism in the primary immune organs of the chick: assays of drug activation, P450 expression, and aldehyde dehydrogenase.环磷酰胺在雏鸡主要免疫器官中的代谢：药物活化、细胞色素P450表达及醛脱氢酶的测定

Arch Toxicol. 1991;65(1):32-8. doi: 10.1007/BF01973500.