Kulabukhova T K, Shubnikova E A
Biull Eksp Biol Med. 1980 Aug;90(8):224-7.
Insulin-like protein (ILP) was extracted from the submaxillary glands of cats, guinea-pigs and male rabbits. As shown by radioimmunoassay, it is localized in the cells of the striated ducts of the salivary tubes. ILP is likely to be related to small granules visible under electron microscope. These granules are largely located in the apical parts of the cells. The amount of ILP (immunoreactive insulin per Ig crude weight of the glands was determined. The content of immunoreactive insulin was found to be higher in submaxillary glands (over than by 60 times) as compared with blood serum but less than in the pancreas. The electrophoretic properties of ILP are similar to those of reference human and bovine insulin. It is suggested that the submaxillary glands participate in the maintenance of insular homeostasis.
胰岛素样蛋白（ILP）是从猫、豚鼠和雄性兔子的颌下腺中提取的。放射免疫分析表明，它定位于唾液管横纹管的细胞中。ILP可能与电子显微镜下可见的小颗粒有关。这些颗粒主要位于细胞的顶端部分。测定了ILP的含量（每克腺体粗重的免疫反应性胰岛素）。发现颌下腺中免疫反应性胰岛素的含量比血清高（超过60倍），但比胰腺中的少。ILP的电泳特性与参考人胰岛素和牛胰岛素的电泳特性相似。有人认为颌下腺参与胰岛内环境稳定的维持。
