Gibbs C J, Amyx H L, Bacote A, Masters C L, Gajdusek D C
J Infect Dis. 1980 Aug;142(2):205-8. doi: 10.1093/infdis/142.2.205.
Kuru and Creutzfeldt-Jakob disease of humans and scrapie disease of sheep and goats were transmitted to squirrel monkeys (Saimiri sciureus) that were exposed to the infectious agents only by their nonforced consumption of known infectious tissues. The asymptomatic incubation period in the one monkey exposed to the virus of kuru was 36 months; that in the two monkeys exposed to the virus of Creutzfeldt-Jakob disease was 23 and 27 months, respectively; and that in the two monkeys exposed to the virus of scrapie was 25 and 32 months, respectively. Careful physical examination of the buccal cavities of all of the monkeys failed to reveal signs or oral lesions. One additional monkey similarly exposed to kuru has remained asymptomatic during the 39 months that it has been under observation.
人类的库鲁病和克雅氏病以及绵羊和山羊的羊瘙痒病，通过仅让松鼠猴（松鼠猴属）非强制食用已知感染性组织而将感染源传播给了它们。暴露于库鲁病病毒的一只猴子的无症状潜伏期为36个月；暴露于克雅氏病病毒的两只猴子的无症状潜伏期分别为23个月和27个月；暴露于羊瘙痒病病毒的两只猴子的无症状潜伏期分别为25个月和32个月。对所有猴子的口腔进行仔细体格检查，未发现体征或口腔病变。另一只同样暴露于库鲁病的猴子在接受观察的39个月期间一直无症状。
