成年鸡骨髓中终末红系成熟系列上鸡胎儿抗原的表达
Chicken fetal antigen expression on the definitive erythroid maturation series in the bone marrow of the adult chicken.
作者信息
Nelson C H, Patel N H, Sanders B G
出版信息
J Exp Zool. 1980 Apr;212(1):101-8. doi: 10.1002/jez.1402120113.
Chicken fetal antigen (CFA) describes a membrane developmental antigen system present on embryonic and fetal erythroid cells that is present during development, but is absent on erythrocytes of mature chickens. In this study, CFA was detected by indirect immunofluorescence and correlated with six stages of morphological maturation of erythroid cells. All cells in the erythroid series through the late polychromatic erythrocyte (reticulocyte) stage were found to possess CFA. Fluorescent intensity and staining patterns of the definitive erythroid series demonstrated CFA concentration increase and distribution pattern change throughout erythroid maturation.
鸡胚胎抗原（CFA）是一种存在于胚胎和胎儿红细胞上的膜发育抗原系统，在发育过程中存在，但在成熟鸡的红细胞上不存在。在本研究中，通过间接免疫荧光检测CFA，并将其与红细胞形态成熟的六个阶段相关联。发现红系中直至晚幼红细胞（网织红细胞）阶段的所有细胞都具有CFA。成熟红细胞系的荧光强度和染色模式表明，在整个红细胞成熟过程中，CFA浓度增加且分布模式发生变化。
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