Mannweiler E, Stumpf J, Felgner P, Lederer I
Dtsch Med Wochenschr. 1978 Oct 6;103(40):1562-5. doi: 10.1055/s-0028-1129301.
Serum samples of 66 persons who had eaten meat from a wild boar were tested two to three times within 11 months for antibodies against extracts from Trichinella larvae. Watery extract of Trichinella spiralis larvae served as antigen. Complement-fixation was of little use because of its lack of sensitivity. Indirect haemagglutination and the ELISA test (enzyme-linked immunosorbent assay) gave uncertain results only in individual cases. There was a relationship between the clinical picture and the mean antibody concentration, clearer in the ELISA test than the indirect haemagglutination one. A fall in antibody titre was observed within the period of observation in only one third of patients. Results with sera of control subjects were of only limited use in relation to the specificity of the demonstrated antibodies.
对66名食用过野猪肉的人员的血清样本，在11个月内进行了两到三次检测，以检测针对旋毛虫幼虫提取物的抗体。旋毛虫幼虫的水性提取物用作抗原。由于补体结合试验缺乏敏感性，其用途不大。间接血凝试验和酶联免疫吸附测定（ELISA）仅在个别情况下给出不确定的结果。临床症状与平均抗体浓度之间存在关联，ELISA试验比间接血凝试验更明显。在观察期内，仅三分之一的患者抗体滴度下降。对照受试者血清的检测结果对于所证实抗体的特异性来说，用途有限。
