Saathoff M, Kasper M, Demmer H
Dtsch Med Wochenschr. 1978 Oct 13;103(41):1606-11. doi: 10.1055/s-0028-1129309.
Serum samples of humans and animals with Trichinella infection of different duration and severity were analysed for Trichinella antibodies by four different serological methods. The indirect immunofluorescence test and the indirect haemagglutination test proved to be the most sensitive ones. Complement-fixation reaction gave the poorest results. In fresh Trichinella infections the heterologous antibody against cercaria of S. mansoni was more strongly developed than the homologous antibody which is effective in the microprecision test on Trichinella larvae. Although the animals deliberately infected also had, at the beginning of infection, a marked reaction to cercaria, this test became negative earlier than the microprecipitation test. Differentiation of Trichinella from Schistosoma infections is serologically possible without difficulty by means of adult schistosomes. The cross-reaction observed between T. spiralis and various Filaria types can be differentiated with adult O. volvulus as antigen.
采用四种不同的血清学方法，对不同感染持续时间和严重程度的旋毛虫感染的人和动物血清样本进行了旋毛虫抗体分析。间接免疫荧光试验和间接血凝试验被证明是最敏感的方法。补体结合反应结果最差。在旋毛虫新鲜感染中，针对曼氏血吸虫尾蚴的异源抗体比在旋毛虫幼虫微量精确试验中有效的同源抗体发展得更强。虽然故意感染的动物在感染开始时对尾蚴也有明显反应，但该试验比微量沉淀试验更早呈阴性。借助成虫血吸虫，在血清学上不难区分旋毛虫感染和血吸虫感染。以盘尾丝虫成虫为抗原，可以区分旋毛虫与各种丝虫类型之间观察到的交叉反应。
