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白色念珠菌中的天冬氨酸、丙氨酸、谷氨酸、苹果酸葡萄糖-6-磷酸脱氢酶

[Aspartate, alanine, glutamate, malate glucose-6-phosphate dehydrogenases in Candida albicans].

作者信息

Tsinberg M B, Suleĭmanov K G, Olifson L E

出版信息

Mikrobiologiia. 1980 Jul-Aug;49(4):578-83.

PMID:6997704
Abstract

Multiple molecular forms of aspartate, alanine, glutamate, malate and glucose-6-phosphate dehydrogenases were studied in the course of Candida albicans growth using electrophoresis in polyacrylamide gel. The isozyme spectrum and the activity of dehydrogenases were found to depend on the cultural age and the cofactor being used (NAD or NADP). The protein-antigenic spectrum and the composition of multiple molecular forms of dehydrogenases were compared in C. albicans in the course of its growth in order to characterize more completely the properties of the culture at a certain growth phase.

摘要

利用聚丙烯酰胺凝胶电泳,研究了白色念珠菌生长过程中天冬氨酸、丙氨酸、谷氨酸、苹果酸和葡萄糖-6-磷酸脱氢酶的多种分子形式。发现脱氢酶的同工酶谱和活性取决于培养时间和所使用的辅因子(NAD或NADP)。为了更全面地表征白色念珠菌在特定生长阶段的培养特性,对其生长过程中脱氢酶的蛋白质抗原谱和多种分子形式的组成进行了比较。

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