Schwerk W, Braum B
Dtsch Med Wochenschr. 1978 Oct 20;103(42):1643-7. doi: 10.1055/s-0028-1129314.
116 patients with clinically suspected obstructive jaundice were subjected to primary sonographic examination by means of the "real-time" method to differentiate between intrahepatic (internal) and extrahepatic (surgical) cholestasis. Diagnosis was finally confirmed by observing the clinical course, by further examinations, and in 63 cases by surgery or PM. Sonographic examination revealed the direct cause of the extrahepatic obstruction in 82 of 87 patients (94.3%) with extrahepatic cholestasis; in case of dilatation of the bile duct, the approximate site of the obstruction could be determined. In about 75% of the cases, the cause of biliary obstruction was correctly identified. Intrahepatic tumours or metastases were present in 10 of 27 patients with intrahepatic cholestasis; sonographic identification was effected in all cases and histologically or cytologically confirmed with aspiration material from fine-needle biopsies. The high accuracy and uncomplicated technique avoiding discomfort or harm to the patient, make sonography a useful method in differential diagnosis of cholestasis.
116例临床疑似梗阻性黄疸的患者接受了“实时”超声检查,以区分肝内(内科性)和肝外(外科性)胆汁淤积。最终通过观察临床病程、进一步检查以及63例患者的手术或尸检确诊。超声检查揭示了87例肝外胆汁淤积患者中82例(94.3%)肝外梗阻的直接原因;在胆管扩张的情况下,可以确定梗阻的大致部位。在大约75%的病例中,正确识别了胆道梗阻的原因。27例肝内胆汁淤积患者中有10例存在肝内肿瘤或转移;所有病例均通过超声检查识别,并通过细针穿刺活检的抽吸材料进行组织学或细胞学确诊。超声检查准确性高且技术简单,避免了给患者带来不适或伤害,使其成为胆汁淤积鉴别诊断的一种有用方法。