Colby T V, Hunt S, Pelzmann K, Carrington C B
Respiration. 1980;39(5):295-9. doi: 10.1159/000194232.
We have presented the clinical, radiologic and pathologic features of 2 patients with pulmonary malakoplakia. The histologic features, including diagnositc Michaelis-Gutmann bodies, were identical to those in the urinary tract where malakoplakia is recognized as an abnormal cellular response to chronic bacterial infection. Both patients were immunocompromised: one a cardiac transplant, the other a patient with Hodgkin's disease. The lesions were focal and showed some response to antibiotic therapy, although other disease processes progressed in both patients. Malakoplakia should be added to the list of unusual infections occurring at unusual sites in compromised hosts.
我们报告了2例肺软斑病患者的临床、放射学及病理学特征。其组织学特征，包括诊断性的迈克尔is-古特曼小体，与尿路软斑病相同，在尿路中软斑病被认为是对慢性细菌感染的一种异常细胞反应。两名患者均存在免疫功能低下：一名是心脏移植患者，另一名是霍奇金病患者。病变为局灶性，对抗生素治疗有一定反应，尽管两名患者的其他疾病进程仍在发展。软斑病应被列入免疫功能低下宿主在不寻常部位发生的罕见感染名单中。
