Szołkowska Małgorzata, Langfort Renata, Szczepulska Ewa M, Bestry Iwona, Religioni Jarosław
Zakład Patomorfologii, Instytut Gruźlicy i Chorób Płuc, ul. Płocka 26, 01-138 Warszawa, Poland.
Pneumonol Alergol Pol. 2007;75(4):398-404.
Malakoplakia is a rare, chronic, granulomatous disease seen in immunocompromised patients, caused by multiple infectious agents, most often bacteria. Microscopically, accumulations of macrophages with granular cytoplasm and intra- or extracellular structures, called Michaelis-Gutmann bodies are characteristic. Main cause of pulmonary malakoplakia is Rhodococcus equi infection. We report two cases of pulmonary malakoplakia, in one case R. equi infection was confirmed. We also present a summary of recent knowledge about the pathogenesis, morphology and clinical course of the disease.
马勒科波拉病是一种罕见的慢性肉芽肿性疾病，见于免疫功能低下的患者，由多种感染因子引起，最常见的是细菌。在显微镜下，具有颗粒状细胞质的巨噬细胞以及细胞内或细胞外结构（称为米氏小体）的聚集是其特征。肺部马勒科波拉病的主要病因是马红球菌感染。我们报告了两例肺部马勒科波拉病病例，其中一例确诊为马红球菌感染。我们还总结了关于该疾病的发病机制、形态学和临床过程的最新知识。
