Deysine M, Leiblich N, Rubenstein R, Rosario E
Surg Gynecol Obstet. 1980 Oct;151(4):477-80.
The observation that severe clinical bacterial infections are associated with decreases in total serum albumin levels was confirmed in experiments involving dogs and rats. In rodents, the injection of methylprednisolone sodium succinate after the onst of the infection significantly reduced the decrease in the serum albumin values. However, this protective or corrective effect did not occur if the steroid was given prior to the infection. The effect of cortisone may be due to its capacity to stimulate albumin synthesis by the parenchyma of the liver.
在涉及狗和大鼠的实验中证实了严重临床细菌感染与血清总白蛋白水平降低相关这一观察结果。在啮齿动物中，感染开始后注射琥珀酸钠甲泼尼龙可显著减少血清白蛋白值的降低。然而，如果在感染前给予类固醇，则不会出现这种保护或纠正作用。可的松的作用可能是由于其刺激肝脏实质合成白蛋白的能力。
