Hinz E, Domm S
Tropenmed Parasitol. 1980 Jun;31(2):135-42.
Experimental infection of mother mice by intraperitoneal injection of Echinococcus multilocularis cyst material does not result in the transfer of protective immunity to the offspring. In the contrary, if infected via the same route, filial mice show a lower antibody titer, when examined 36, 78 and 120 days p.i. and a higher worm burden (average: 1455 mg) in comparison with control mice born of non-infected mothers (average parasite weight: 844 mg). The question is discussed, whether these observations are due to the suppressive action of transferred antibodies or whether the offspring become immunologically tolerant by the transfer of parasite antigen.
通过腹腔注射多房棘球绦虫囊肿材料对母鼠进行实验性感染，并不会将保护性免疫传递给后代。相反，如果通过相同途径感染，与未感染母亲所生的对照小鼠相比，子代小鼠在感染后36、78和120天检测时抗体滴度较低，虫体负荷较高（平均：1455毫克）（对照小鼠平均寄生虫重量：844毫克）。文中讨论了这些观察结果是由于转移抗体的抑制作用，还是子代通过寄生虫抗原的转移而产生免疫耐受。
