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[抗生素和防腐剂对蛋白酶纤溶活性的影响]

[Effect of antibiotics and antiseptics on the fibrinolytic activity of proteases].

作者信息

Chepcheruk G S, Kostiuchenko A L, Radaev A A

出版信息

Vestn Khir Im I I Grek. 1980 Jun;124(6):79-82.

PMID:6998084
Abstract

A table of compatibility of proteases and antibacterial drugs was developed on the basis of investigation of fibrinolytic effect of proteolytic enzymes (fibrinolysine, chimotrypsin, streptokinase, terrilitin) and their combinations with most popular antibiotics and antiseptic solutions. According to the data of the authors, terrilitin and streptokinase are most efficient of the proteolytic enzymes studied and less dependent upon antibiotics and antiseptic solutions when used in combinations.

摘要

基于对蛋白水解酶(纤维蛋白溶酶、胰凝乳蛋白酶、链激酶、特立菌素)的纤溶作用及其与最常用抗生素和防腐溶液组合的研究,编制了一份蛋白酶与抗菌药物的配伍表。根据作者的数据,在所研究的蛋白水解酶中,特立菌素和链激酶最为有效,且在联合使用时对抗生素和防腐溶液的依赖性较小。

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