Otto H F, Gebbers J O, Bettmann I
Schweiz Med Wochenschr. 1980 Jul 8;110(27-28):1043-5.
The histology and immunohistology of 22 malignant lymphomas of the intestinal tract have been studied using the so-called "Kiel classification". We have found 12 lymphomas with low grade malignancy (lymphocytic, lympho-plasmocytoid, centrocytic, centroblastic-centrocytic) and 10 with high grade (centroblastic, lymphoblastic, immunoblastic). In all cases of lympho-plasmocytoid and immunoblastic lymphoma a monoclonal pattern of intracellular immunoglobulin was identified by the immunoperoxidae method. This technique offers considerable help in distinguishing between (monoclonal) malignant lymphomas and (polyclonal) lympho- or immunoproliferative processes.
我们运用所谓的“基尔分类法”对22例肠道恶性淋巴瘤的组织学和免疫组织学进行了研究。我们发现12例低度恶性淋巴瘤(淋巴细胞性、淋巴浆细胞样、中心细胞性、中心母细胞-中心细胞性)和10例高度恶性淋巴瘤(中心母细胞性、淋巴母细胞性、免疫母细胞性)。在所有淋巴浆细胞样和免疫母细胞性淋巴瘤病例中,通过免疫过氧化物酶法鉴定出细胞内免疫球蛋白的单克隆模式。这项技术在区分(单克隆)恶性淋巴瘤和(多克隆)淋巴或免疫增殖过程方面提供了很大帮助。