自发性高血压大鼠血压升高与肾髓质前列腺素E2缺乏无关。
Increased blood pressure in the SHR is not related to a deficit in renomedullary PGE2.
作者信息
Stygles V G, Reinke D A, Rickert D E, Hook J B
出版信息
Experientia. 1978 Aug 15;34(8):1025-6. doi: 10.1007/BF01915324.
PMID:700013
Abstract
Synthesis of prostaglandin E2 by renal medulla from SHR and WKY rats was compared during early postnatal development. Although arterial blood pressure was significantly higher in SHR as early as 6 weeks of age, no difference in renal medullary prostaglandin synthesis was observed.
摘要
在出生后早期发育过程中，比较了自发性高血压大鼠（SHR）和Wistar-Kyoto大鼠（WKY）肾髓质中前列腺素E2的合成情况。尽管早在6周龄时SHR的动脉血压就显著更高，但未观察到肾髓质前列腺素合成有差异。
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