短期去势-肾上腺切除术后大鼠垂体前叶各细胞类型对雌激素的体内摄取情况。
In vivo estrogen uptake by individual cell types of the rat anterior pituitary after short-term castration-adrenalectomy.
作者信息
Keefer D A
出版信息
Cell Tissue Res. 1980;209(1):167-75. doi: 10.1007/BF00219933.
PMID:7000362
Abstract
In vivo estrogen uptake was measured in five anterior pituitary cell types of the rat by a quantitative autoradiographic-immunocytochemical technique. In male and female rats that had been castrated and adrenalectomized for one day all five cell types showed nuclear concentration of label one hour after injection of 3H-estradiol. The order of labeling intensity was lactotropes > somatotropes > gonadotropes > corticotropes > thyrotropes. No significant overall sex difference in estrogen uptake was apparent although male pituitaries tended to take up slightly more. Physiological correlates to these data are discussed.
摘要
采用定量放射自显影-免疫细胞化学技术，对大鼠的五种垂体前叶细胞类型中的体内雌激素摄取情况进行了测定。在切除睾丸和肾上腺一天的雄性和雌性大鼠中，注射3H-雌二醇一小时后，所有五种细胞类型均显示出标记物的核内聚集。标记强度顺序为：催乳细胞>生长激素细胞>促性腺激素细胞>促肾上腺皮质激素细胞>促甲状腺激素细胞。尽管雄性垂体的摄取量略多，但雌激素摄取方面并无明显的总体性别差异。文中讨论了这些数据的生理相关性。
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