Rowley A F, Ratcliffe N A
Immunology. 1980 Jul;40(3):483-92.
The effect of naturally occurring haemagglutinins on the in vitro phagocytosis of sheep erythrocytes by the blood cells (haemocytes) of Clitumnus extradentatus and Periplaneta americana was studied. The results showed that the haemagglutinins in both species failed to act as opsonins. Indeed, in some instances, incubation of erythrocytes in haemolymph resulted in less avid ingestion as compared with the saline-incubated controls. This reduced phagocytosis was probably caused by the clumping of erythrocytes on the haemocyte monolayers, leaving fewer single red cells available for uptake. The possible roles of these erythrocyte agglutinins in the host defence systems of insects are discussed.
研究了天然存在的血凝素对无齿水螅（Clitumnus extradentatus）和美洲大蠊（Periplaneta americana）血细胞（血淋巴细胞）体外吞噬绵羊红细胞的影响。结果表明，这两个物种中的血凝素均不能作为调理素。实际上，在某些情况下，与用盐水孵育的对照相比，红细胞在血淋巴中的孵育导致吞噬活性降低。这种吞噬作用的降低可能是由于红细胞在血淋巴细胞单层上聚集，导致可供摄取的单个红细胞减少所致。讨论了这些红细胞凝集素在昆虫宿主防御系统中的可能作用。
