Zitting A, Falck K, Skyttä E
Int Arch Occup Environ Health. 1980;47(1):47-52. doi: 10.1007/BF00378327.
The aerosol fraction of the oxidative thermal decomposition products (700 degrees C) of rigid polyurethane foam was collected on glass fiber filters and fractionated into either-soluble neutral, acidic, and basic fractions and water-soluble compounds. The fractions showed mutagenic activity in a bacterial fluctuation test with Salmonella typhimurium TA98 or Escherichia coli CM891 as the tester strains. All the fractions induced mutations in both strains after metabolic activation with rat liver S-9 mix. The basic and the water-soluble fractions were mutagenic for S. typhimurium TA 98 even without activation. Thin-layer chromatography showed the presence of several primary aromatic amines in the aerosol. Polycyclic aromatic hydrocarbons were not detected by glass capillary gas chromatogaphy.
将硬质聚氨酯泡沫塑料的氧化热分解产物（700摄氏度）的气溶胶部分收集在玻璃纤维滤器上，并分离成可溶中性、酸性和碱性部分以及水溶性化合物。这些部分在以鼠伤寒沙门氏菌TA98或大肠杆菌CM891作为测试菌株的细菌波动试验中表现出致突变活性。在用大鼠肝脏S-9混合物进行代谢活化后，所有部分在两种菌株中均诱导出突变。即使没有活化，碱性部分和水溶性部分对鼠伤寒沙门氏菌TA 98也具有致突变性。薄层色谱显示气溶胶中存在几种伯芳香胺。玻璃毛细管气相色谱未检测到多环芳烃。
