Batrak G E, Zakopka V M
Farmakol Toksikol. 1978 Sep-Oct;41(5):533-7.
Tests conducted with dogs by using Pavlov's method of conditioned reflexes (salivation procedure) showed fluothane to act on the central nervous system 3 times as strong as does ether. This is confirmed by a longer time necessary for the higher nervous system to normalize. Thus, awakening of the animals after the ether anesthesia, the re-establishment of the conditioned reflex activity supervened by the 7th day on the average, whereas, after the fluothane anesthesia, this occurred only on the 24th day.