Patrick J, Challis J
Semin Perinatol. 1980 Oct;4(4):275-86.
Real-time scanners have permitted investigators to measure fetal breathing movements during pregnancy in humans. It has been demonstrated that fetal breathing movements are episodic and occur about 30% of the time during the last 10 wk of pregnancy. Design of studies must account for the episodic nature of fetal breathing movements. It will be important to account for the relationship of fetal breathing movements to maternal meals, time of day, and gestational age of fetuses. Furthermore, cigarette smoking, alcohol, and drugs may alter fetal breathing measurements. Finally, fetal breathing movements are absent during accelerated labor and may normally be diminished during the last 3 days prior to spontaneous term labor. Measurement of fetal breathing movements using real-time scanners has helped to understand circadian rhythms in fetal life and may ultimately be of use in the assessment of fetal health. It is important that much more information be obtained concerning factors that normally influence fetal breathing movements before proper strategies can be suggested for the use of these measurements in the clinical assessment of fetal health.
实时扫描仪使研究人员能够测量人类孕期胎儿的呼吸运动。已证实胎儿呼吸运动是间歇性的，在妊娠最后10周期间约占30%的时间。研究设计必须考虑到胎儿呼吸运动的间歇性。考虑胎儿呼吸运动与母亲进餐、一天中的时间以及胎儿胎龄之间的关系很重要。此外，吸烟、饮酒和药物可能会改变胎儿呼吸测量结果。最后，在加速分娩期间胎儿呼吸运动会消失，在自然足月分娩前的最后3天通常也会减弱。使用实时扫描仪测量胎儿呼吸运动有助于了解胎儿生命中的昼夜节律，最终可能用于评估胎儿健康。在能够提出将这些测量用于胎儿健康临床评估的适当策略之前，获取更多有关正常影响胎儿呼吸运动的因素的信息非常重要。
