Patrick J, Campbell K, Carmichael L, Natale R, Richardson B
Obstet Gynecol. 1980 Jul;56(1):24-30.
Continuous measurements of human fetal breathing movements and gross fetal body movements were made with an ultrasonic real-time scanner for periods of 24 houro 31 weeks' gestation, a significant increase in fetal breathing movements occurred during the second and third hours after meals; this pattern apparently followed an increase in maternal plasma glucose concentrations. At 38 to 39 weeks' gestation, fetal breathing movements increased during the second and third hours after breakfast, but the troughs seen before lunch and supper at 30 to 31 weeks' gestation were not present. Fetal breathing movements diminished over the day and reached a minimum between 1900 and 2400 hours. Fetal breathing activity increased in both groups between 0400 and 0700 hours while mothers were asleep; this was not related to an increase in maternal glucose concentrations. Absence of fetal breathing movements was observed for up to 122 minutes in this analysis of 480 hours in 20 patients. These data show that much more information must be obtained on factors that normally influence fetal breathing activity. Only then can research strategies be suggested for clinical evaluation of the usefulness of fetal breathing movements in the assessment of fetal health.
使用超声实时扫描仪对人类胎儿呼吸运动和胎儿大体身体运动进行了连续测量，测量时间为妊娠31周时的24小时。在餐后第二和第三个小时，胎儿呼吸运动显著增加；这种模式显然是随着母体血浆葡萄糖浓度的升高而出现的。在妊娠38至39周时，早餐后第二和第三个小时胎儿呼吸运动增加，但在妊娠30至31周时午餐和晚餐前出现的低谷并不存在。胎儿呼吸运动在一天中逐渐减少，在19:00至24:00之间达到最低水平。在母亲睡眠期间，两组胎儿的呼吸活动在04:00至07:00之间均有所增加；这与母体葡萄糖浓度的升高无关。在对20名患者480小时的分析中，观察到胎儿呼吸运动停止长达122分钟。这些数据表明，必须获取更多关于正常影响胎儿呼吸活动因素的信息。只有这样，才能提出研究策略，用于临床评估胎儿呼吸运动在评估胎儿健康方面的有用性。
