Betina V
Folia Microbiol (Praha). 1980;25(6):505-23. doi: 10.1007/BF02897219.
Numerous antibodies with a known mechanism of action are utilized as possible means for studying morphogenesis and differentiation. Inhibitors of biosynthesis of nucleic acids and proteins, compounds intervening with the synthesis and/or function of cell walls and membranes or compounds influencing the energy metabolism are particularly useful. The use of antibiotics for studies of the life cycle of viruses, bacteria, fungi, myxomycetes, protozoa and algae is analyzed in the present communication. Certain aspects of morphogenesis and functions of mitochondria and plastids were clarified with the aid of antibiotics. Relationships between production of antibiotics and differentiation of their producers are discussed in the final part of the paper.
许多作用机制已知的抗体被用作研究形态发生和分化的可能手段。核酸和蛋白质生物合成抑制剂、干扰细胞壁和细胞膜合成及/或功能的化合物或影响能量代谢的化合物特别有用。本文分析了抗生素在研究病毒、细菌、真菌、黏菌、原生动物和藻类生命周期中的应用。借助抗生素阐明了线粒体和质体形态发生及功能的某些方面。本文最后一部分讨论了抗生素的产生与其产生者分化之间的关系。
