在动物模型中测量的牙科植入材料的生物相容性。

The biocompatibility of dental implant materials measured in an animal model.

作者信息

Garcia D A, Sullivan T M, O'Neill D M

出版信息

J Dent Res. 1981 Jan;60(1):44-9. doi: 10.1177/00220345810600010801.

DOI:10.1177/00220345810600010801

Abstract

The biocompatibility of two implant materials, vitallium and poly-methyl methacrylate (PMMA), was evaluated in an animal model in which bone formation and resorption are independent of each other. Neither material accelerated resorption, but formation was inhibited 12% by vitallium and 38% by PMMA. When three PMMA preparations varying in monomer content were tested, the data exhibited a dose-response relation, suggesting that inhibition of bone formation was due to the presence of residual monomer.

摘要

在一个骨形成和吸收相互独立的动物模型中，对两种植入材料（钴铬合金和聚甲基丙烯酸甲酯（PMMA））的生物相容性进行了评估。两种材料均未加速吸收，但钴铬合金使骨形成受到12%的抑制，聚甲基丙烯酸甲酯则使其受到38%的抑制。当对三种单体含量不同的聚甲基丙烯酸甲酯制剂进行测试时，数据呈现出剂量反应关系，这表明骨形成受到抑制是由于残留单体的存在。