Odashima S
Oncology. 1980;37(4):282-6. doi: 10.1159/000225453.
A number of papers relating N-nitroso compounds as carcinogens for experimental animals and man was reviewed. These summerized in (1) early works, (2) amines and sodium nitrite, (3) disease models, (4) species susceptible to nitrosamines, (5) target organs, (6) strain specificity, (7) individual specificity and (8) minimum carcinogenic dose. Through these literature references and the results of animal experiments in the author's own laboratory on various acylated N-nitroso compounds, the possibility that various preformed nitrosamines in the environment, as well as those which are formed in our body, can cause tumors of various organs in human body is highly suggested.
综述了一系列将N-亚硝基化合物作为实验动物和人类致癌物的论文。这些内容总结在：（1）早期研究；（2）胺类与亚硝酸钠；（3）疾病模型；（4）对亚硝胺敏感的物种；（5）靶器官；（6）品系特异性；（7）个体特异性；以及（8）最小致癌剂量。通过这些文献参考以及作者自己实验室对各种酰化N-亚硝基化合物进行的动物实验结果，强烈表明环境中各种预先形成的亚硝胺以及在我们体内形成的亚硝胺可能会导致人体各种器官的肿瘤。
