Healy G B
Otolaryngol Clin North Am. 1980;13(3):483-8.
Malignant tumors of the head and neck in childhood can present a perplexing diagnostic and therapeutic challenge. The advent of advanced chemotherapeutic and radiotherapeutic techniques has both enhanced survival rates and changed the role of surgical intervention in many of the tumors in this age group. Recent studies employing an interdisciplinary approach have demonstrated that mutilating surgery for head and neck tumors can often be avoided. A prolonged disease free survival and a probable cure can be anticipated in 50 to 70 per cent of the patients. Higher survival rates have been achieved in some tumors, such as stage I Hodgkin's disease and localized rhabdomyosarcoma in some series. The surgeon plays a key role in delineating and diagnosing the initial disease. He must also be attentive to regular follow-up, inasmuch as many patients frequently die of local recurrence, which may go undetected in early stages if vigilance is not maintained. All members of the treatment team must exercise regular conscientious surveillance if these devastating problems are to be overcome.
儿童头颈部恶性肿瘤会带来令人困惑的诊断和治疗挑战。先进的化疗和放疗技术的出现提高了生存率，并改变了手术干预在该年龄组许多肿瘤中的作用。最近采用多学科方法的研究表明，头颈部肿瘤的致残性手术通常可以避免。50%至70%的患者有望实现长期无病生存并可能治愈。在一些肿瘤中已取得了更高的生存率，如某些系列中的Ⅰ期霍奇金病和局限性横纹肌肉瘤。外科医生在明确和诊断初始疾病方面起着关键作用。他还必须注意定期随访，因为许多患者常死于局部复发，如果不保持警惕，早期可能无法发现。如果要克服这些严重问题，治疗团队的所有成员都必须定期进行认真的监测。
