Hermel B
Polim Med. 1980;10(1):3-18.
Corneal incision employed according to Paufique's method for microsurgical cataract removal was dressed with cyanoacrylic adhesive Histoacryl n-blau after the previous wound filling with biological adhesive from freeze dried human plasma. The experiments were performed on 80 enucleated cattle eyeballs and on 60 eyeballs of rabbits. The material were divided into groups depending on the method of wound dressing. In the I group wounds were dressed with adaptation sutures according to the Liegard method and filled with biological adhesive; cyanoacrylic adhesive was applied supplementary. In the II group wounds were filled with biological adhesive and sutured. In the III group wounds were only sutured. The rabbits were observed for 21 days and the resistance of wound anastomosis examined. In the I group wound resistance immediately after the operation and after 24 hours was found to be two times higher than in other groups. 7 days after the operation the values obtained in all groups were similar. In all groups the eyeballs irritation was similar within the first five days. 7 days after the operation plates of cyanoacrylic adhesive were removed without difficulties. In all groups linear corneal scars with mistiness 2 mm wide was found, also singular blood vessels penetrating the cornea were observed.
根据保菲克法进行显微手术白内障摘除时所做的角膜切口，在先前用冻干人血浆生物粘合剂填充伤口后，用氰基丙烯酸粘合剂Histoacryl n - blau进行包扎。实验在80个摘除的牛眼球和60个兔眼球上进行。根据伤口包扎方法将材料分组。在第一组中，按照利加德法用适配缝线包扎伤口并填充生物粘合剂；另外还使用氰基丙烯酸粘合剂。在第二组中，伤口填充生物粘合剂并缝合。在第三组中，伤口仅进行缝合。对兔子观察21天，并检查伤口吻合处的抗阻力。发现第一组术后立即及术后24小时的伤口抗阻力比其他组高两倍。术后7天，所有组获得的值相似。在所有组中，头五天内眼球刺激情况相似。术后7天，氰基丙烯酸粘合剂板顺利取出。在所有组中均发现有2毫米宽模糊的线性角膜瘢痕，还观察到有单个血管穿透角膜。
