Komissarenko V P, Gordienko V M, Turchin I S, Cherniavskaia I B
Tsitol Genet. 1980 Mar-Apr;14(2):3-6.
A-, B- and D-insulocytes were revealed when studying the monolayer cell culture of guinea pig pancreatic islands with electron microscope. With an increase in cultivation time (3 days) the cytoplasm ultrastructure in all the cell types changes, the number of secretory granules in B-cells decreases. At later periods (10 days) the signs of secretory cells degeneration and dedifferentiation are observed.
在用电子显微镜研究豚鼠胰岛单层细胞培养物时,发现了A、B和D胰岛细胞。随着培养时间的增加(3天),所有细胞类型的细胞质超微结构都会发生变化,B细胞中分泌颗粒的数量会减少。在后期(10天),会观察到分泌细胞变性和去分化的迹象。