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[甲状腺上皮性肿瘤病理解剖学研究中的紧迫问题]

[Pressing problems in the study of the pathological anatomy of epithelial thyroid gland tumors].

作者信息

Zaridze D G

出版信息

Arkh Patol. 1980;42(11):60-70.

PMID:7004412
Abstract

The paper analyses most important publications and the author's own observations on the pathology of the thyroid gland epithelial tumours. The WHO Histological classification of tumours of the thyroid gland was used for the analysis of the material, although on the basis of his own studies the author concludes that apart from the benign thyroid gland tumours mentioned in the classification, atypical and papillary adenomas, adenoma of Ashkinazi cells and benign tumour consisting of C-cells should be distinguished. In the morphological diagnosis of highly differentiated carcinoma tumours the greatest importance is attributed to the structure of the nucleus of tumour cells the structure of which have been studied both by light and electron microscopy. The latter is also very important for histogenetic diagnosis of undifferentiated carcinoma and tumours consisting of C-cells. The tumour cells rich in mitochondria in which the activity of oxidative-reductive enzymes is high are considered as cells undergoing degeneration due to cytotoxic effect of lymphocytes.

摘要

本文分析了关于甲状腺上皮肿瘤病理学的最重要出版物以及作者自己的观察结果。材料分析采用了世界卫生组织的甲状腺肿瘤组织学分类,不过作者基于自身研究得出结论,除了该分类中提及的甲状腺良性肿瘤外,还应区分非典型和乳头状腺瘤、阿什肯纳齐细胞腺瘤以及由C细胞组成的良性肿瘤。在高分化癌肿瘤的形态学诊断中,肿瘤细胞核的结构最为重要,其结构已通过光学显微镜和电子显微镜进行了研究。后者对于未分化癌和由C细胞组成的肿瘤的组织发生学诊断也非常重要。富含线粒体且氧化还原酶活性高的肿瘤细胞被认为是由于淋巴细胞的细胞毒性作用而发生变性的细胞。

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