用17β-雌二醇处理且未出现血浆促黄体生成素激增的产后母羊垂体对促黄体生成素释放激素的反应性

Pituitary responsiveness to LH-RH in post-partum ewes treated with oestradiol-17 beta and failing to show a plasma LH surge.

作者信息

Wright P J, Stelmasiak T, Chamley W A

出版信息

Aust J Biol Sci. 1980 Aug;33(4):465-9. doi: 10.1071/bi9800465.

DOI:10.1071/bi9800465

Abstract

Oestradiol-17 beta (40 micrograms intravenously) failed to elicit a surge in plasma LH levels by 13 h after administration in 64% (16 out of 25) Merino ewes about 30 days post partum in the anoestrous season. LH-RH responsiveness and LH-RH priming effect were significantly greater in these ewes than in similar post-partum (n = 9) and non-parturient ewes (n = 3) not treated with oestradiol. This suggests that the failure of the oestrogen-positive feedback effect on LH release in post-partum ewes is not due to a failure of oestradiol action on the pituitary increasing pituitary responsiveness to LH-RH and LH-RH priming effect, but could be due to inadequate release of LH-RH from the hypothalamus.

摘要

在产后约30天的乏情季节，给25只美利奴母羊静脉注射17β-雌二醇（40微克），64%（25只中的16只）的母羊在给药后13小时血浆促黄体生成素（LH）水平未出现激增。这些母羊的促性腺激素释放激素（LH-RH）反应性和LH-RH激发效应显著高于未用雌二醇处理的类似产后母羊（n = 9）和未产母羊（n = 3）。这表明产后母羊中雌激素对LH释放的正反馈作用失败，并非由于雌二醇对垂体的作用失败，即垂体对LH-RH的反应性和LH-RH激发效应未增加，而是可能由于下丘脑LH-RH释放不足。

相似文献

1

Pituitary responsiveness to LH-RH in post-partum ewes treated with oestradiol-17 beta and failing to show a plasma LH surge.用17β-雌二醇处理且未出现血浆促黄体生成素激增的产后母羊垂体对促黄体生成素释放激素的反应性

Aust J Biol Sci. 1980 Aug;33(4):465-9. doi: 10.1071/bi9800465.

2

Pitutary responsiveness to LH-RH, the occurrence of oestradiol- 17 beta-induced LH-positive feedback and the resumption of oestrous cycles in ewes post partum.垂体对促黄体生成素释放激素（LH-RH）的反应性、17β-雌二醇诱导的促黄体生成素（LH）正反馈的发生以及产后母羊发情周期的恢复。

J Reprod Fertil. 1980 Sep;60(1):171-6. doi: 10.1530/jrf.0.0600171.

3

Evidence for a change in oestradiol negative feedback and LH pulse frequency in post-partum ewes.产后母羊雌二醇负反馈和促黄体生成素脉冲频率变化的证据。

J Reprod Fertil. 1981 Jan;61(1):97-102. doi: 10.1530/jrf.0.0610097.

4

Effects of modifying gonadotrophin-releasing hormone input before and after the oestrogen-induced LH surge in ovariectomized ewes with hypothalamo-pituitary disconnection.下丘脑-垂体切断的去卵巢母羊在雌激素诱导的促黄体生成素峰之前和之后改变促性腺激素释放激素输入的影响。

J Endocrinol. 1990 Nov;127(2):223-33. doi: 10.1677/joe.0.1270223.

5

Pulsatile administration of gonadotrophin-releasing hormone stimulates, in oestrogen-treated anaesthetized ovariectomized ewes, a surge release of LH qualitatively and quantitatively different from that induced by oestradiol in conscious ovariectomized ewes.在经雌激素处理的麻醉去卵巢母羊中，脉冲式给予促性腺激素释放激素所刺激引起的促黄体生成素（LH）高峰释放，在性质和数量上与在清醒去卵巢母羊中由雌二醇诱导产生的不同。

J Endocrinol. 1988 Jan;116(1):143-8. doi: 10.1677/joe.0.1160143.

6

Effect of adrenocorticotrophic hormone (ACTH1-24) on ovine pituitary gland responsiveness to exogenous pulsatile GnRH and oestradiol-induced LH release in vivo.促肾上腺皮质激素（ACTH1-24）对绵羊垂体在体内对外源性脉冲式促性腺激素释放激素（GnRH）的反应性及雌二醇诱导的促黄体生成素（LH）释放的影响。

Anim Reprod Sci. 1999 Apr 30;55(3-4):193-203. doi: 10.1016/s0378-4320(99)00023-8.

7

Effect of transport on pituitary responsiveness to exogenous pulsatile GnRH and oestradiol-induced LH release in intact ewes.运输对完整母羊垂体对外源性脉冲式促性腺激素释放激素（GnRH）的反应性及雌二醇诱导的促黄体生成素（LH）释放的影响。

J Reprod Fertil. 1999 May;116(1):9-18. doi: 10.1530/jrf.0.1160009.

8

LH release and luteal function in post-partum acyclic ewes after the pulsatile administration of LH-RH.产后无发情周期母羊在脉冲式给予促黄体生成素释放激素（LH-RH）后的促黄体生成素释放及黄体功能

J Reprod Fertil. 1983 Mar;67(2):257-62. doi: 10.1530/jrf.0.0670257.

9

Priming effect of luteinizing hormone releasing hormone in the hypogonadal mouse.促性腺激素释放激素对性腺功能减退小鼠的启动效应。

J Endocrinol. 1982 Aug;94(2):283-7. doi: 10.1677/joe.0.0940283.

10

Effect of oestrogen and an LH-RH agonist on the release of gonadotrophins in ovariectomized ewes deprived of LH-RH.雌激素和促黄体生成素释放激素（LH-RH）激动剂对切除卵巢且缺乏促黄体生成素释放激素（LH-RH）的母羊促性腺激素释放的影响。

J Reprod Fertil. 1981 May;62(1):131-40. doi: 10.1530/jrf.0.0620131.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。