Silagadze D G, Beletskaia L V, Kolesnikova V Iu, Gnezditskaia E V, Liampert I M
Biull Eksp Biol Med. 1980 Nov;90(11):575-7.
Indirect immunofluorescence with the use of antibodies) to group A streptococcal polysaccharide (A-polysaccharide has shown cross-reacting antigen (CRA) common for A-polysaccharide and the squamous epithelium to be localized, apart from the skin and thymus, in basal layer cells of oral mucosa epithelium, esophagus, inferior portion of the rectum, in salivary and mammary ducts. These tissue carriers of CRA are united by common ectodermal origin. The evidence obtained may be of use in the devising of a method for differential diagnosis of tumors of different genesis. In the course of organogenesis CRA appears early in the monolayer embryonic epithelium. The data presented correlate with those obtained before during study of animal tissues.
使用针对A组链球菌多糖(A-多糖)的抗体进行间接免疫荧光检测显示,除皮肤和胸腺外,A-多糖与鳞状上皮的交叉反应抗原(CRA)定位于口腔黏膜上皮、食管、直肠下部的基底层细胞以及唾液腺和乳腺导管中。这些CRA的组织载体具有共同的外胚层起源。所获得的证据可能有助于设计一种鉴别不同起源肿瘤的诊断方法。在器官发生过程中,CRA在单层胚胎上皮中早期出现。所呈现的数据与之前在动物组织研究中获得的数据相关。