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通过转移因子将瘤型麻风患者的反应转化为麻风菌素和麻风结节菌素。

Conversion of reactions to leprolin and lepromin in patients with lepromatous leprosy by the transfer factor.

作者信息

Han S H, Tsai L C, Hu S C, Loo S T

出版信息

Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1980 Mar;13(1):1-8.

PMID:7004800
Abstract

Conversion of leprolin and early lepromin reactions was achieved by two injections of transfer factor made of lymphocytes from lepromin-positive tuberculoid leprosy patients. However, the late reaction to lepromin remained unchanged. The importance of the degree of sensitivity of the cell donor was demonstrated, and a booster dose was also found to be useful. The feasibility of using transfer factor in treatment of lepromatous leprosy is briefly discussed.

摘要

通过注射两剂由麻风菌素阳性结核样型麻风患者淋巴细胞制成的转移因子,实现了麻风菌素反应和早期麻风菌素反应的转化。然而,对麻风菌素的迟发反应保持不变。证明了细胞供体敏感程度的重要性,还发现追加剂量是有用的。简要讨论了使用转移因子治疗瘤型麻风的可行性。

相似文献

1
Conversion of reactions to leprolin and lepromin in patients with lepromatous leprosy by the transfer factor.通过转移因子将瘤型麻风患者的反应转化为麻风菌素和麻风结节菌素。
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1980 Mar;13(1):1-8.
2
Skin test activity of an antigen fraction prepared from Mycobacterium leprae compared with standard lepromin and tuberculin PPD in leprosy patients.将从麻风分枝杆菌制备的抗原组分与标准麻风菌素和结核菌素PPD在麻风病患者中的皮肤试验活性进行比较。
Lepr Rev. 1984 Mar;55(1):33-40. doi: 10.5935/0305-7518.19840004.
3
A placebo controlled clinical trial of transfer factor in lepromatous leprosy.一项关于转移因子治疗瘤型麻风病的安慰剂对照临床试验。
Clin Exp Immunol. 1979 Jan;35(1):45-52.
4
Comparative study of skin reactions in leprosy patients to M. leprae-lepromin and to ICRC-in, an antigen from cultivable acid-fast bacilli from M. leprae isolated from lepromatous nodules.麻风病患者对麻风杆菌麻风菌素和ICRC-in(一种从麻风结节中分离出的可培养抗酸杆菌的抗原)皮肤反应的比较研究。
Lepr India. 1977 Oct;49(4):472-84.
5
T lymphocyte reactivity of leprosy patients and healthy contacts from a leprosy-endemic population to delipidified cell components of Mycobacterium leprae.
Lepr Rev. 1994 Mar;65(1):34-44. doi: 10.5935/0305-7518.19940003.
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Early and late reactions in tuberculoid and lepromatous leprosy patients with lepromins from Mycobacterium leprae and five selected cultivable mycobacteria.麻风分枝杆菌和五种选定可培养分枝杆菌的麻风菌素对结核样型和瘤型麻风患者的早期和晚期反应。
Lepr India. 1978 Oct;50(4):566-71.
7
Skin test response to M. leprae precursor coccoid organisms in a high leprosy endemic area as compared to lepromin.与麻风菌素相比,麻风高流行地区对麻风杆菌前体细胞样生物体的皮肤试验反应。
Lepr India. 1981 Oct;53(4):566-79.
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Evaluation of cell mediated immunity in the histopathologic spectrum of leprosy using lymphocyte transformation test.利用淋巴细胞转化试验评估麻风病组织病理学谱中的细胞介导免疫。
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Immunological profiles of leprosy patients and healthy family contacts toward M. leprae antigens.麻风病患者及健康家庭接触者对麻风杆菌抗原的免疫特征。
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Comparison of various preparations of Mycobacterium leprae and other mycobacteria by lymphocyte stimulation.通过淋巴细胞刺激比较麻风分枝杆菌和其他分枝杆菌的各种制剂。
Int J Lepr Other Mycobact Dis. 1978 Jul-Dec;46(3-4):386-93.