Weghaupt K
Fortschr Med. 1978 Sep 7;96(33):1629-34.
A survey of the results attained by the most prominent authors of the individual therapy methods is given. After electro-resection and -coagulation of the vulvar tumor followed by roentgen or telecobalt irradiation, patients are almost without pain. The primary mortality in 332 patients was 1,5% (= 5 cases) because lymphonodectomy was performed in only 66 cases (20%). The period of hospitalization lasts about four weeks and cosmetic healing is excellent. This therapy method can also be recommended for largely extended tumors as lack of local symptoms can be achieved up to 97%. Of the 332 patients treated at our hospital, almost equal numbers of patients were seen with carcinoma stage I and II and stage III and IV. In stage I and II (negative lymph nodes) 74,5% and in stage III and IV (positive lymph nodes) 38,4% were cured. 80% were aged between 61 and 90 years. In spite of this negative selection of patients which was also combined with the intercurrent mortality rate of 13% (= 43 cases), 193 of the 332 patients or 58,1% survived five years or longer. In the last five years the survival rate was even 62,2%. A survey of the results obtained by electrocoagulation in the last 30 years is given. Especially the enormous increase of high risks as diabetes (42,2%) and the great number of over-aged patients (83,3%) are emphasized.
本文综述了各主要个体化治疗方法所取得的成果。对外阴肿瘤进行电切除和电凝治疗后,再进行X射线或钴远距离照射,患者几乎无疼痛。332例患者的原发性死亡率为1.5%(即5例),因为仅66例(20%)患者进行了淋巴结切除术。住院时间约为四周,美容效果极佳。这种治疗方法也可推荐用于大面积扩展的肿瘤,因为局部症状缓解率可达97%。在我院接受治疗的332例患者中,I期和II期癌以及III期和IV期癌患者数量几乎相等。在I期和II期(淋巴结阴性)患者中,治愈率为74.5%;在III期和IV期(淋巴结阳性)患者中,治愈率为38.4%。80%的患者年龄在61岁至90岁之间。尽管患者存在这种不利选择,且并发死亡率为13%(即43例),但332例患者中有193例(58.1%)存活了五年或更长时间。在过去五年中,存活率甚至达到了62.2%。本文还综述了过去30年中电凝治疗所取得的成果。尤其强调了高风险因素大幅增加,如糖尿病患者占比42.2%,以及老年患者数量众多(83.3%)。