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未经治疗的麻风病病例的巨噬细胞培养物。

Macrophage culture from untreated leprosy cases.

作者信息

Veliath A J, Bedi B M, Balasubrahmanyan M

出版信息

Lepr India. 1980 Apr;52(2):203-8.

PMID:7005539
Abstract

Macrophage cultures from the peripheral blood were performed in 25 untreated bacteraemic leprosy patients. The monocytes on conversion to macrophages in culture continued to harbour solidly stained M. Leprae till the termination of culture. It is suggested that the majority of these bacilli are viable and capable of multiplication intracellularly in macrophages if cultures could be maintained for sufficiently long periods. It was observed that bacteraemia in Leprosy can be detected by the culture technic. It has been found to be more sensitive than the leukocyte adherence method.

摘要

对25例未经治疗的菌血症麻风患者的外周血进行巨噬细胞培养。培养过程中单核细胞转化为巨噬细胞后,仍持续含有染色牢固的麻风杆菌,直至培养结束。有人提出,如果培养时间足够长,这些杆菌中的大多数是有活力的,并且能够在巨噬细胞内繁殖。据观察,麻风菌血症可通过培养技术检测到。已发现它比白细胞黏附法更敏感。

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Macrophage culture from untreated leprosy cases.未经治疗的麻风病病例的巨噬细胞培养物。
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