Plasmocytoma is generally a systemic disorder and has to be differentiated from solitary plasmocytoma of bones and connective tissue. Diagnosis is based on the typical bone marrow findings, the demonstration of monoclonal paraprotein and the radiological skeletal changes. Prognosis is poor, life expectancy limited to about 18 months. Specific therapy with cytotoxic drugs leads in many cases to marked improvement of the general condition, relative freedom of pain and a decreased complication rate.
浆细胞瘤通常是一种全身性疾病，必须与骨和结缔组织的孤立性浆细胞瘤相鉴别。诊断基于典型的骨髓检查结果、单克隆副蛋白的证实以及骨骼的放射学改变。预后较差，预期寿命限制在约18个月。使用细胞毒性药物进行特异性治疗在许多情况下可使全身状况显著改善、疼痛相对缓解且并发症发生率降低。
