碳霉素，一种大环内酯类抗生素。

Carbomycin, a macrolide antibiotic.

作者信息

Ashy M A, Khalil A E, Abou-Zeid A A

出版信息

Zentralbl Bakteriol Naturwiss. 1980;135(6):541-51. doi: 10.1016/s0323-6056(80)80075-9.

Abstract

Carbomycin is produced by Streptomyces halstedii. It was produced in a medium containing the following ingredients (g/l): soybean meal, 30.0; glucose, 22.0; NaCl, 1.0; CaCO3, 5.0; CoCl2 . 6 H2O, 0.005; and lard oil, 4.0. Influence of trace elements on the biosynthesis of carbomycin was recorded. Methods of extraction and purification were given in the review article. Chemical and physical properties of carbomycin were also described. A microbiological assay method for carbomycin determination was described. Biosynthesis of carbomycin was reported. Mechanism of action of carbomycin on micro-organisms was also given in the review article.

摘要

碳霉素由哈氏链霉菌产生。它是在含有以下成分（克/升）的培养基中产生的：豆粕，30.0；葡萄糖，22.0；氯化钠，1.0；碳酸钙，5.0；六水合氯化钴，0.005；以及猪油，4.0。记录了微量元素对碳霉素生物合成的影响。综述文章中给出了提取和纯化方法。还描述了碳霉素的化学和物理性质。描述了一种用于测定碳霉素的微生物测定方法。报道了碳霉素的生物合成。综述文章中也给出了碳霉素对微生物的作用机制。