Papasozomenos S, Shapiro S
Cancer. 1981 Jan 1;47(1):99-103. doi: 10.1002/1097-0142(19810101)47:1<99::aid-cncr2820470117>3.0.co;2-z.
A low-grade astrocytoma confined to the pineal gland is reported. The neoplasm was incidentally found at autopsy in a 39-year-old white female with no neurologic symptoms. The astrocytic origin of the neoplasm has been confirmed with electron microscopic studies and with peroxidase-antiperoxidase immunostaining, using an antiserum raised against the glial fibrillary acidic (GFA) protein. This is the first published case of a well-documented astrocytoma limited to the pineal. The presence of apparently normal, GFA protein-containing cells in human pineal gland is also demonstrated for the first time.
本文报道了一例局限于松果体的低级别星形细胞瘤。该肿瘤是在一名39岁无神经系统症状的白人女性尸检时偶然发现的。通过电子显微镜研究以及使用针对胶质纤维酸性蛋白（GFA）的抗血清进行过氧化物酶-抗过氧化物酶免疫染色，证实了该肿瘤的星形细胞起源。这是首例有充分文献记载的局限于松果体的星形细胞瘤。同时也首次证明了人松果体中存在明显正常的含GFA蛋白的细胞。
