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大鼠松果体间质细胞中S-100蛋白和胶质纤维酸性蛋白的免疫组织化学显示

Immunohistochemical demonstration of S-100 protein and GFA protein in interstitial cells of rat pineal gland.

作者信息

Møller M, Ingild A, Bock E

出版信息

Brain Res. 1978 Jan 20;140(1):1-13. doi: 10.1016/0006-8993(78)90234-2.

Abstract

The presence of the glial marker proteins, the S-100 and the glial fibrillary acidic (GFA) protein, in the pineal gland was investigated in the rat. Using both the indirect peroxidase-labelled immunoglobulin technique and the unlabelled antibody enzyme (PAP) method, we observed few scattered S-100 and GFA positive cells in the pineal. The number, location and morphology of these cells suggest they are the pineal interstitial cells. This indicates that the interstitial cells are of neuroectodermal origin, possibly macroglial cells themselves.

摘要

在大鼠中研究了松果体中神经胶质标记蛋白S-100和神经胶质纤维酸性蛋白(GFA)的存在情况。使用间接过氧化物酶标记免疫球蛋白技术和未标记抗体酶(PAP)方法,我们观察到松果体中有少量散在的S-100和GFA阳性细胞。这些细胞的数量、位置和形态表明它们是松果体间质细胞。这表明间质细胞起源于神经外胚层,可能本身就是大胶质细胞。

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