大肠杆菌热稳定肠毒素活性的分解代谢物阻遏
Catabolite repression of Escherichia coli heat-stable enterotoxin activity.
作者信息
Martínez-Cadena M G, Guzman-Verduzco L M, Stieglitz H, Kupersztoch-Portnoy Y M
出版信息
J Bacteriol. 1981 Feb;145(2):722-8. doi: 10.1128/jb.145.2.722-728.1981.
Abstract
The Escherichia coli heat-stable enterotoxin (ST) coded for by plasmid pYK007 (Apr ST+) showed a dependence for cyclic adenosine 3',5'-monophosphate (cAMP) to express ST activity in an adenyl cyclase (cya) deletion mutant; no ST activity was detected in the presence of cAMP in a cAMP receptor protein (crp) deletion mutant or in a double deletion mutant (delta cya delta crp). The cya-crp effect on ST activity could not be accounted for by a modification of the copy number of plasmid deoxyribonucleic acid per chromosome equivalent or by an alteration in the secretion of an active intracellular enterotoxin.
摘要
由质粒pYK007编码的大肠杆菌热稳定肠毒素（ST）（Apr ST +）在腺苷酸环化酶（cya）缺失突变体中表现出对环磷酸腺苷（cAMP）的依赖性以表达ST活性；在cAMP受体蛋白（crp）缺失突变体或双缺失突变体（δcyaδcrp）中，存在cAMP时未检测到ST活性。cya-crp对ST活性的影响不能通过每条染色体等效物中质粒脱氧核糖核酸拷贝数的改变或活性细胞内肠毒素分泌的改变来解释。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Catabolite repression.分解代谢物阻遏
Cold Spring Harb Symp Quant Biol. 1961;26:249-56. doi: 10.1101/sqb.1961.026.01.031.
3
ADENOSINE 3',5'-PHOSPHATE IN ESCHERICHIA COLI.大肠杆菌中的3',5'-磷酸腺苷
J Biol Chem. 1965 Mar;240:1309-14.
4
Genetic regulatory mechanisms in the synthesis of proteins.蛋白质合成中的遗传调控机制。
J Mol Biol. 1961 Jun;3:318-56. doi: 10.1016/s0022-2836(61)80072-7.
5
Hybridization between Escherichia coli and Shigella.大肠杆菌与志贺氏菌之间的杂交。
J Bacteriol. 1957 Oct;74(4):461-76. doi: 10.1128/jb.74.4.461-476.1957.
6
Linkage of heat-stable enterotoxin activity and ampicillin resistance in a plasmid isolated from an Escherichia coli strain of human origin.从一株源自人类的大肠杆菌中分离出的质粒上热稳定肠毒素活性与氨苄青霉素抗性的连锁关系。
Infect Immun. 1980 Nov;30(2):617-20. doi: 10.1128/iai.30.2.617-620.1980.
7
A proposal for a uniform nomenclature in bacterial genetics.细菌遗传学统一命名法的提议。
Genetics. 1966 Jul;54(1):61-76. doi: 10.1093/genetics/54.1.61.
8
Cyclic 3'5-AMP: stimulation of beta-galactosidase and tryptophanase induction in E. coli.环3',5'-腺苷酸：对大肠杆菌中β-半乳糖苷酶的刺激作用及色氨酸酶的诱导
Biochem Biophys Res Commun. 1968 Mar 27;30(6):656-64. doi: 10.1016/0006-291x(68)90563-9.
9
Response of the rabbit ileal loop to cell-free products from Escherichia coli enteropathogenic for swine.兔回肠袢对猪致病性大肠杆菌无细胞产物的反应。
J Infect Dis. 1970 Feb;121(2):182-7. doi: 10.1093/infdis/121.2.182.
10
Replication of a bacterial plasmid and an episome in Escherichia coli.细菌质粒和附加体在大肠杆菌中的复制。
Biochemistry. 1970 Jan 20;9(2):399-406. doi: 10.1021/bi00804a029.
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