Tricot G J, Zwaan F E, Kauffmann R H, Jansen J, Haak H L
Scand J Haematol. 1980 Sep;25(3):264-7. doi: 10.1111/j.1600-0609.1981.tb01399.x.
A 19-year-old male, suffering from post-hepatitis aplastic anaemia, was transplanted with bone marrow cells from his HLA-identical, MLC non-reactive brother. Haematological recovery ensued, but the patient also developed grade IV graft-versus-host disease (GVHD). In addition to involvement of skin, liver and gut, the kidney seemed affected by GVHD since the patient has hypokalaemia and severe hyperkaluria. Other causes of urinary potassium loss were excluded. The amount of potassium loss correlated well with the severity of the GVH-reaction. Although coagulation disorders prohibited a kidney biopsy, the clinical course suggested GVHD to be the cause of the urinary potassium loss.
一名19岁男性，患有肝炎后再生障碍性贫血，接受了来自其HLA相同、混合淋巴细胞培养无反应的兄弟的骨髓细胞移植。随后出现血液学恢复，但患者也发生了IV级移植物抗宿主病（GVHD）。除了皮肤、肝脏和肠道受累外，肾脏似乎也受到GVHD影响，因为患者出现低钾血症和严重高钾尿症。排除了其他导致尿钾丢失的原因。钾丢失量与GVH反应的严重程度密切相关。尽管凝血障碍妨碍了肾活检，但临床病程提示GVHD是尿钾丢失的原因。
