Suppr超能文献

骨生成诱导(对“骨移植”概念的批判性评论)(作者译)

[Osteogenetic induction (critical comments to the concept "bone graft") (author's transl)].

作者信息

de Souza-Ramos R

出版信息

Z Orthop Ihre Grenzgeb. 1980 Oct;118(5):781-7. doi: 10.1055/s-2008-1053538.

Abstract

The author makes an attempt to prove the following facts on the basis of his histological studies: 1. The mechanical process of cutting out small bone fragments from the outer cortex of the long bones of fragments from the outer cortex of the long bones of living humans results in an immediate devitalisation or emptying of the lacunae. 2. In almost 74% of the cases, there is an emptying of the lacunae or absence of the mature osteocytes, as well as degeneration--albeit to a varying degree--in almost 95% of the remaining osteocytes. 3. These facts, i.e. immediate devitalisation of these small fragments of living bones, prompted the author to question the expression "bone graft", even with free or floating bone fragments taken from the same patient, i.e. also with the socalled autogenic or autologus bone grafts. 4. Transplanting or grafting a living bone fragment from the donor area to a recipient area will stimulate the recipient area to form new bones. In this manner, it is possible to achieve osteogenetic induction, and expression which respresents the course of facts with biological accuracy. 5. The mature osteocyte does not participate as a living cell in the osteogenetic process of rehabilitation, does not multiply, and dies. 6. The new bone is shaped by the recipient and not by the grafted bone of the donor.

摘要

作者试图基于其组织学研究证明以下事实

  1. 从活人长骨外皮质切下小骨碎片的机械过程会导致陷窝立即失去活力或空虚。2. 在几乎74%的病例中,陷窝空虚或成熟骨细胞缺失,并且在几乎95%的其余骨细胞中存在不同程度的退变。3. 这些事实,即这些活骨小碎片立即失去活力,促使作者质疑“骨移植”这一表述,即使是取自同一患者的游离或漂浮骨碎片,即所谓的自体骨移植。4. 将活骨碎片从供体区域移植到受体区域会刺激受体区域形成新骨。通过这种方式,可以实现成骨诱导,这一表述以生物学准确性反映了实际过程。5. 成熟骨细胞不作为活细胞参与修复的成骨过程,不增殖并死亡。6. 新骨由受体形成,而非供体的移植骨形成。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验