Sulyok E, Varga F, Csaba I F, Németh M, Tényi I, Györy E, Ertl T
Acta Paediatr Acad Sci Hung. 1980;21(2-3):153-7.
To assess the influences of intrauterine growth retardation on the electrolyte status and the activity of renin-angiotensin-aldosterone system of newborn infants, sodium and potassium balance, as well as plasma renin activity, plasma aldosterone concentration and urinary aldosterone excretion were determined simultaneously in a group of healthy growth retarded and healthy normally grown neonates. It was observed that intake, urinary excretion and retention rate of sodium and potassium as well as the plasma sodium and potassium levels were essentially the same in the two groups. Similarly, no significant difference was found in plasma renin activity, plasma aldosterone level and urinary aldosterone excretion between the neonates whose birth weight was small or appropriate for gestational age. It is concluded that intrauterine growth retardation has no significant influence on the electrolyte status and the activity of the renin--angiotensin--aldosterone system, suggesting that in the regulation of these functions gestational factors are mainly involved.
为评估宫内生长迟缓对新生儿电解质状态及肾素 - 血管紧张素 - 醛固酮系统活性、钠和钾平衡的影响，我们同时测定了一组健康的生长迟缓新生儿和健康的正常生长新生儿的血浆肾素活性、血浆醛固酮浓度及尿醛固酮排泄量。结果发现，两组新生儿钠和钾的摄入量、尿排泄量及潴留率，以及血浆钠和钾水平基本相同。同样，出生体重低或适于胎龄的新生儿之间，血浆肾素活性、血浆醛固酮水平及尿醛固酮排泄量也未发现显著差异。由此得出结论，宫内生长迟缓对电解质状态及肾素 - 血管紧张素 - 醛固酮系统活性无显著影响，这表明在这些功能的调节中，主要涉及的是孕期因素。
